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Many countries in West Asia, defined in this study as the Arabic-speaking countries of the Arabian Peninsula plus Turkey and Iran, have enacted environmental conservation laws but regional underlying drivers of environment change, such as rising incomes and fast-growing populations, continue to put pressure on remaining wetlands. This paper aims to inform conservation efforts by presenting the first regional assessment of the economic value of coastal and freshwater wetlands in West Asia. Using scenario analysis we find that, dependent on the discount rate used, the present value of the regional economic loss of not protecting wetlands by 2050 is between US dollar 2.3 billion and US dollar 7.2 billion (expressed in 2007 US dollars). The method used for this assessment, however, is not suitable for expressing national realities adequately. We therefore suggest that detailed localized studies are conducted to improve insight into the drivers and the social and economic effects of wetland loss in West Asia.